Paul Smits Selected Research

VU 0405652

12/2005

Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability.

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Paul Smits Research Topics

Disease

15	Inflammation (Inflammations) 12/2015 - 08/2003
9	Ischemia 01/2012 - 01/2002
8	Sepsis (Septicemia) 12/2015 - 10/2004
8	Endotoxemia 09/2012 - 01/2005
8	Reperfusion Injury 01/2012 - 01/2005
7	Insulin Resistance 01/2016 - 02/2002
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2017 - 03/2002
6	Hypertension (High Blood Pressure) 05/2013 - 10/2002
5	Essential Hypertension 11/2013 - 02/2002
5	Infarction (Infarctions) 01/2012 - 01/2005
5	Type 2 Diabetes Mellitus (MODY) 09/2011 - 02/2009
5	Hypoglycemia (Reactive Hypoglycemia) 08/2006 - 03/2002
4	Heart Failure 10/2010 - 05/2006
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2016 - 03/2006
3	Septic Shock (Toxic Shock Syndrome) 09/2011 - 12/2005
3	Atherosclerosis 02/2009 - 10/2002
3	Hyperhomocysteinemia 01/2005 - 08/2003
2	Chilblains (Chilblain) 03/2017 - 01/2016
2	Edema (Dropsy) 01/2016 - 03/2006
2	Hyperinsulinism (Hyperinsulinemia) 10/2011 - 03/2006
2	Myocardial Infarction 06/2011 - 05/2009
2	Obesity 02/2011 - 07/2007
2	Coronary Disease (Coronary Heart Disease) 01/2011 - 02/2009
2	Autonomic Dysreflexia 12/2010 - 03/2010
2	Coronary Artery Disease (Coronary Atherosclerosis) 05/2007 - 10/2002
2	Shock 12/2005 - 12/2002
2	Homocystinuria 01/2005 - 01/2005
1	Myocarditis (Carditis) 10/2017
1	Leukemia 01/2015
1	Neoplasms (Cancer) 05/2013
1	Overweight 03/2012
1	Hyperbilirubinemia 02/2011

Drug/Important Bio-Agent (IBA)

19	Adenosine (Adenocard)FDA LinkGeneric 12/2015 - 02/2002
11	Glucose (Dextrose)FDA LinkGeneric 01/2015 - 02/2002
7	Vasoconstrictor AgentsIBA 11/2013 - 06/2002
7	Purinergic P1 Receptors (Adenosine Receptor)IBA 09/2012 - 08/2003
7	Norepinephrine (Noradrenaline)FDA LinkGeneric 06/2007 - 02/2002
6	Insulin (Novolin)FDA Link 02/2011 - 02/2002
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2012 - 06/2009
5	Caffeine (No Doz)FDA LinkGeneric 01/2011 - 02/2002
5	CytokinesIBA 01/2011 - 12/2002
4	Dipyridamole (Persantine)FDA LinkGeneric 01/2011 - 02/2002
4	Purinergic P1 Receptor AntagonistsIBA 01/2011 - 03/2002
4	Epinephrine (Adrenaline)FDA LinkGeneric 05/2004 - 02/2002
3	Vasodilator Agents (Vasodilators)IBA 01/2016 - 10/2010
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2013 - 12/2005
3	EndotoxinsIBA 09/2011 - 12/2004
3	NucleosidesIBA 01/2011 - 07/2005
3	HomocysteineIBA 01/2011 - 01/2005
3	Hypoglycemic Agents (Hypoglycemics)IBA 08/2006 - 03/2002
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2006 - 07/2004
3	AlbuminsIBA 04/2006 - 07/2002
3	Hydrocortisone (Cortisol)FDA LinkGeneric 07/2003 - 02/2002
2	Adrenergic Receptors (Adrenergic Receptor)IBA 09/2017 - 03/2010
2	Arginine (L-Arginine)FDA Link 01/2016 - 03/2006
2	RelaxinIBA 11/2013 - 03/2012
2	Adrenergic Agents (Adrenergic Drugs)IBA 11/2013 - 03/2010
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 03/2012 - 07/2004
2	Atorvastatin (Lipitor)FDA Link 01/2012 - 11/2010
2	PhosphatidylserinesIBA 06/2011 - 05/2007
2	Pharmaceutical PreparationsIBA 02/2011 - 01/2002
2	CholesterolIBA 01/2011 - 02/2009
2	Coffee FDA Link 01/2011 - 02/2009
2	Rosuvastatin Calcium (Crestor)FDA Link 10/2010 - 06/2009
2	Rosiglitazone (Avandia)FDA Link 04/2010 - 03/2006
2	Proteins (Proteins, Gene)FDA Link 05/2007 - 01/2003
2	Methotrexate (Mexate)FDA LinkGeneric 02/2007 - 05/2006
2	Potassium Channels (Potassium Channel)IBA 11/2006 - 10/2004
2	Nitric Oxide Synthase (NO Synthase)IBA 08/2006 - 03/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2006 - 12/2002
2	Annexin A5IBA 07/2005 - 01/2005
2	KATP ChannelsIBA 03/2005 - 01/2003
2	S-AdenosylhomocysteineIBA 01/2005 - 01/2005
2	Theophylline (Theon)FDA LinkGeneric 07/2003 - 03/2002
2	Glyburide (Glibenclamide)FDA LinkGeneric 01/2003 - 01/2002
2	Adenosine Triphosphate (ATP)IBA 01/2003 - 01/2002
2	Cortisone FDA Link 11/2002 - 02/2002
1	Biomarkers (Surrogate Marker)IBA 10/2017
1	Betamethasone (Celestone)FDA Link 03/2017
1	Betamethasone Valerate (Betamethasone 17 Valerate)FDA LinkGeneric 03/2017
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2017
1	heme arginateIBA 01/2016
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2016
1	Heme (Haem)IBA 01/2016
1	Nifedipine (Adalat)FDA LinkGeneric 01/2016
1	EnzymesIBA 01/2015
1	Angiogenesis InhibitorsIBA 05/2013
1	Bevacizumab (Avastin)FDA Link 05/2013
1	Peptide Receptors (Peptide Receptor)IBA 03/2012
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 03/2012
1	AICA ribonucleotide (ZMP)IBA 10/2011
1	VildagliptinIBA 09/2011
1	Blood Glucose (Blood Sugar)IBA 09/2011
1	Type 2 Angiotensin ReceptorIBA 06/2011
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 06/2011
1	Angiotensin II Type 1 Receptor BlockersIBA 06/2011
1	Irbesartan FDA LinkGeneric 06/2011
1	Type 1 Angiotensin ReceptorIBA 06/2011

Therapy/Procedure

5	Therapeutics 06/2010 - 03/2002
1	Aftercare (After-Treatment) 06/2011